Modelling Multiple Sclerosis In Vitro and the Influence of Activated Macrophages
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چکیده
منابع مشابه
P136: The Role of Th1 Lymphocytes in the Pathogenesis of Multiple Sclerosis (MS)
Th1 lymphocytes produce cytokines such as IL-2, IFN-γ, and TNF-α, TNF-β and GM-CSF and play an important role in the increase of delaying sensitivity and defense against intracellular pathogens. IFN-γ is the most important Th1 cell cytokine that induces the production of IgG, activation of macrophages,enhancing phagocytosis, and also increasing MHC class I and class II mo...
متن کاملP170: The Role of Th1 Lymphocytes in The Pathogenesis of Multiple Sclerosis (MS)
Th1 lymphocytes produce cytokines such as IL-2, IFN-γ, and TNF-α, TNF-β and GM-CSF. IFN-γ is the most important Th1 cell cytokine that induces the production of IgG, activation of macrophages, enhancing phagocytosis, and also increasing MHC class I and class II molecules. Increasing serum level of Th1 cytokines have also been observed in MS patients. It has also been prov...
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Several MRI contrast agents (CAs) are used in medical diagnosis that gadolinium (Gd3+) is the most widely used as contrast agents. Unfortunately, its toxicity is due to its inefficiency. In this review, we discuss about the ability of SPIONs in MRI and application in Multiple Sclerosis diagnosis. Superparamagnetic iron oxide nanoparticles (SPIONs) such as magnetite nanoparticles are used as goo...
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Background and Objectives: Multiple sclerosis (MS) is an autoimmune neurodegenerative disease of the central nervous system (CNS). Although, the contribution of various cells such as B cells, CD8+ T cells, microglia/macrophages, dendritic cells, asterocytes and mast cells in the pathogenesis of MS have been demonstrated, however, it seems that autoreactive myelin specific CD4+ T cells pla...
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